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Anti-MSH6PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-MSH6 Polyclonal Antibody品牌：solarbio | 貨號：K003624P

英文名稱Anti-MSH6 Polyclonal Antibody
宿主Rabbit
別名GTBP;GTMBP;HNPCC5;HSAP;p160
應用WB IF
稀釋比例WB 1:500-1000. IF 1:50-100.
交叉反應 Human Mouse
蛋白分子量153kDa
Gene ID2956
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human MSH6
性狀液體
Public Immunogen RangeRecombinant protein of human MSH6
Subcellular LocationsNucleus
Swiss ProtP52701
克隆類型 Polyclonal Antibody
背景資料This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.

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