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Anti-LPIN1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-LPIN1 Polyclonal Antibody品牌：solarbio | 貨號：K008030P

英文名稱Anti-LPIN1 Polyclonal Antibody
宿主Rabbit
別名PAP1
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-300.
交叉反應(yīng) Human Mouse
蛋白分子量99kDa
Gene ID23175
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human LPIN1
性狀液體
Public Immunogen RangeA synthetic peptide of human LPIN1
Subcellular LocationsNucleus Membrane
Swiss ProtQ14693
克隆類型 Polyclonal Antibody
背景資料This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.

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