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Anti-CAPN10PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CAPN10 Polyclonal Antibody品牌:solarbio | 貨號(hào):K006092P

英文名稱Anti-CAPN10 Polyclonal Antibody
宿主Rabbit
別名CANP10;NIDDM1
應(yīng)用WB
稀釋比例WB 1:1000-4000.
交叉反應(yīng) Human
蛋白分子量75kDa
Gene ID11132
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CAPN10
性狀液體
Public Immunogen RangeRecombinant protein of human CAPN10
Subcellular LocationsCytosol Mitochondrion Plasma Membrane
Swiss ProtQ9HC96
克隆類型 Polyclonal Antibody
背景資料Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.

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