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Anti-BMPR2PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-BMPR2 Polyclonal Antibody品牌:solarbio | 貨號(hào):K006853P

英文名稱(chēng)Anti-BMPR2 Polyclonal Antibody
宿主Rabbit
別名BMR2;PPH1;BMPR3;BRK-3;T-ALK;BMPR-II
應(yīng)用IHC
稀釋比例IHC 1:25-100.
交叉反應(yīng) Human Mouse
蛋白分子量115kDa
Gene ID659
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human BMPR2
性狀液體
Public Immunogen RangeRecombinant protein of human BMPR2
Subcellular LocationsCytoplasm
Swiss ProtQ13873
克隆類(lèi)型 Polyclonal Antibody
背景資料This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

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