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Anti-NDUFV1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-NDUFV1 Polyclonal Antibody品牌:solarbio | 貨號:K005622P

英文名稱Anti-NDUFV1 Polyclonal Antibody
宿主Rabbit
別名CI-51K;CI51KD;UQOR1
應用WB IF
稀釋比例WB 1:500-2000. IF 1:50-100.
交叉反應 Human Mouse Rat
蛋白分子量51kDa
Gene ID4723
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human NDUFV1
性狀液體
Public Immunogen RangeRecombinant protein of human NDUFV1
Subcellular LocationsMitochondrion
Swiss ProtP49821
克隆類型 Polyclonal Antibody
背景資料The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson’s disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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