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公司: 沈陽萬類生物科技有限公司
貨號: WL01992 抗體名: Cleaved caspase-3抗體 抗體英文名: Cleaved caspase-3 antibody 濃度: >1mg/ml 應(yīng)用范圍: WB,IHC 宿主: 兔 適應(yīng)物種: H,M,R,T 標(biāo)記物: 無 克隆性: 否 保存條件: -20℃ 形態(tài): 液體 亞型: IgG 規(guī)格: 50μl(>50μg)
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產(chǎn)品貨號WL01992產(chǎn)品名稱cleaved Caspase-3 Antibody預(yù)測分子量Predicted band size: 20 kDaObserved band size: 17 kDa別名CASP3; CPP32; CPP32B; SCA-1濃度>1 mg/ml免疫原合成Caspase-3多肽抗體來源兔特異性抗人,小鼠,大鼠,兔克隆類型多克隆抗體產(chǎn)品應(yīng)用WB ;IHC成分親和純化抗體,20 mM PBS,150 mM NaCl,100 μg/ml BSA,50%甘油,NaN3<0.02%保存條件-20℃保存背景資料This Caspase-3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. Caspase-3 is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP).
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