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Anti-CTSCPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CTSC Polyclonal Antibody品牌：solarbio | 貨號：K007682P

英文名稱Anti-CTSC Polyclonal Antibody
宿主Rabbit
別名JP;HMS;JPD;PLS;CPPI;DPP1;DPPI;PALS;DPP-I;PDON1
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應(yīng) Human
蛋白分子量52kDa
Gene ID1075
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human CTSC
性狀液體
Public Immunogen RangeA synthetic peptide of human CTSC
Subcellular LocationsCytoplasm
Swiss ProtP53634
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

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