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Anti-ABCB11PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-ABCB11 Polyclonal Antibody品牌：solarbio | 貨號(hào)：K007568P

英文名稱Anti-ABCB11 Polyclonal Antibody
宿主Rabbit
別名BSEP;PGY4;SPGP;ABC16;BRIC2;PFIC2;PFIC-2
應(yīng)用IHC
稀釋比例IHC 1:25-100.
交叉反應(yīng) Human Mouse Rat
蛋白分子量146kDa
Gene ID8647
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human ABCB11
性狀液體
Public Immunogen RangeA synthetic peptide of human ABCB11
Subcellular LocationsCytoplasm
Swiss ProtO95342
克隆類型 Polyclonal Antibody
背景資料The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

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