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Anti-GRM3PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-GRM3 Polyclonal Antibody品牌:solarbio | 貨號(hào):K007505P

英文名稱Anti-GRM3 Polyclonal Antibody
宿主Rabbit
別名GLUR3;mGlu3;GPRC1C;MGLUR3
應(yīng)用WB
稀釋比例WB 1:200-1000.
交叉反應(yīng) Human Mouse Rat
蛋白分子量99kDa
Gene ID2913
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human GRM3
性狀液體
Public Immunogen RangeA synthetic peptide of human GRM3
Swiss ProtQ14832
克隆類型 Polyclonal Antibody
背景資料L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

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