Anti-PRKAR2APolyclonalAntibody-一抗-抗體-蛋白與免疫-耗材-Bio-Rad伯樂官網(wǎng) |伯樂授權(quán)代理 |伯樂ddPCR| 伯樂Aminex| 伯樂層析填料色譜柱

Anti-PRKAR2APolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-PRKAR2A Polyclonal Antibody品牌：solarbio | 貨號：K007141P

英文名稱	Anti-PRKAR2A Polyclonal Antibody
宿主	Rabbit
別名	PKR2;PRKAR2
應(yīng)用	WB IHC
稀釋比例	WB 1:500-2000. IHC 1:35-200.
交叉反應(yīng)	Human
蛋白分子量	46kDa
Gene ID	5576
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human PRKAR2A
性狀	液體
Public Immunogen Range	Recombinant protein of human PRKAR2A
Subcellular Locations	Cytoplasm Cell membrane
Swiss Prot	P13861
克隆類型	Polyclonal Antibody
背景資料	cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).

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