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Anti-GSTA3PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-GSTA3 Polyclonal Antibody品牌:solarbio | 貨號(hào):K007060P

英文名稱(chēng)Anti-GSTA3 Polyclonal Antibody
宿主Rabbit
別名GTA3;GSTA3-3
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應(yīng) Human
蛋白分子量25kDa
Gene ID2940
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human GSTA3
性狀液體
Public Immunogen RangeRecombinant protein of human GSTA3
Subcellular LocationsCytoplasm
Swiss ProtQ16772
克隆類(lèi)型 Polyclonal Antibody
背景資料Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity.

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