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Anti-SETD2PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-SETD2 Polyclonal Antibody品牌:solarbio | 貨號:K006912P

英文名稱Anti-SETD2 Polyclonal Antibody
宿主Rabbit
別名HYPB;SET2;HIF-1;HIP-1;KMT3A;HBP231;HSPC069;p231HBP
應用IHC
稀釋比例IHC 1:50-200.
交叉反應 Human Mouse
蛋白分子量288kDa
Gene ID29072
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human SETD2
性狀液體
Public Immunogen RangeRecombinant protein of human SETD2
Subcellular LocationsNucleus
Swiss ProtQ9BYW2
克隆類型 Polyclonal Antibody
背景資料Huntington’s disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

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