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Anti-PCPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-PC Polyclonal Antibody品牌：solarbio | 貨號：K006815P

英文名稱Anti-PC Polyclonal Antibody
宿主Rabbit
別名PCB
應(yīng)用WB
稀釋比例WB 1:200-1000.
交叉反應(yīng) Human Mouse Rat
蛋白分子量130kDa
Gene ID5091
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human PC
性狀液體
Public Immunogen RangeRecombinant protein of human PC
Subcellular LocationsMitochondrion
Swiss ProtP11498
克隆類型 Polyclonal Antibody
背景資料This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5′ UTRs, but encoding the same protein, have been found for this gene.

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