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Anti-NFKBIDPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-NFKBID Polyclonal Antibody品牌:solarbio | 貨號(hào):K006652P

英文名稱Anti-NFKBID Polyclonal Antibody
宿主Rabbit
別名TA-NFKBH;IkappaBNS
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:25-100.
交叉反應(yīng) Human
蛋白分子量33kDa
Gene ID84807
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human NFKBID
性狀液體
Public Immunogen RangeRecombinant protein of human NFKBID
Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ8NI38
克隆類型 Polyclonal Antibody
背景資料May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

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