Anti-BCCIPPolyclonalAntibody-一抗-抗體-蛋白與免疫-耗材-Bio-Rad伯樂(lè)官網(wǎng) |伯樂(lè)授權(quán)代理 |伯樂(lè)ddPCR| 伯樂(lè)Aminex| 伯樂(lè)層析填料色譜柱

Anti-BCCIPPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-BCCIP Polyclonal Antibody品牌：solarbio | 貨號(hào)：K005929P

英文名稱(chēng)	Anti-BCCIP Polyclonal Antibody
宿主	Rabbit
別名	TOK-1;TOK1
應(yīng)用	WB IHC
稀釋比例	WB 1:500-2000. IHC 1:100-200.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	36kDa
Gene ID	56647
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human BCCIP
性狀	液體
Public Immunogen Range	Recombinant protein of human BCCIP
Subcellular Locations	Nucleus
Swiss Prot	Q9P287
克隆類(lèi)型	Polyclonal Antibody
背景資料	This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

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