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Anti-ACTN2PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-ACTN2 Polyclonal Antibody品牌:solarbio | 貨號:K003686P

英文名稱Anti-ACTN2 Polyclonal Antibody
宿主Rabbit
別名CMD1AA;CMH23
應(yīng)用WB IF
稀釋比例WB 1:500-2000. IF 1:50-200.
交叉反應(yīng) Human Mouse Rat
蛋白分子量104kDa
Gene ID88
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human ACTN2
性狀液體
Public Immunogen RangeRecombinant protein of human ACTN2
Subcellular LocationsCytoplasm Z line myofibril sarcomere
Swiss ProtP35609
克隆類型 Polyclonal Antibody
背景資料Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

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