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Anti-PAK4PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-PAK4 Polyclonal Antibody品牌:solarbio | 貨號(hào):K008214P

英文名稱Anti-PAK4 Polyclonal Antibody
宿主Rabbit
別名KIAA1142;Serine/threonine-protein kinase PAK 4
應(yīng)用WB IHC
稀釋比例WB 1:200-1000. IHC 1:25-100.
交叉反應(yīng) Human Mouse
蛋白分子量64kDa
Gene ID10298
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human PAK4
性狀液體
Public Immunogen RangeRecombinant protein of human PAK4
Subcellular LocationsCytoplasm
Swiss ProtO96013
克隆類型 Polyclonal Antibody
背景資料PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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