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Anti-CTSCPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CTSC Polyclonal Antibody品牌：solarbio | 貨號：K005811P

英文名稱Anti-CTSC Polyclonal Antibody
宿主Rabbit
別名CPPI;DPP-I;DPP1;DPPI;HMS;JP;JPD;PALS;PDON1;PLS
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-100.
交叉反應(yīng) Human Mouse Rat
蛋白分子量52kDa
Gene ID1075
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CTSC
性狀液體
Public Immunogen RangeRecombinant protein of human CTSC
Subcellular LocationsLysosome
Swiss ProtP53634
克隆類型 Polyclonal Antibody
背景資料This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

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