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Anti-CD22PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CD22 Polyclonal Antibody品牌：solarbio | 貨號(hào)：K006342P

英文名稱Anti-CD22 Polyclonal Antibody
宿主Rabbit
別名SIGLEC-2;SIGLEC2
應(yīng)用WB IF
稀釋比例WB 1:500-2000. IF 1:10-100.
交叉反應(yīng) Human Mouse
蛋白分子量95kDa
Gene ID933
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CD22
性狀液體
Public Immunogen RangeRecombinant protein of human CD22
Subcellular LocationsCell membrane Single-pass type I membrane protein
Swiss ProtP20273
克隆類型 Polyclonal Antibody
背景資料Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through.

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