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Anti-GMNNPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-GMNN Polyclonal Antibody品牌:solarbio | 貨號(hào):K003907P

英文名稱Anti-GMNN Polyclonal Antibody
宿主Rabbit
別名Gem;MGORS6
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應(yīng) Human
蛋白分子量24kDa
Gene ID51053
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human GMNN
性狀液體
Public Immunogen RangeRecombinant protein of human GMNN
Subcellular LocationsCytoplasm Nucleus
Swiss ProtO75496
克隆類型 Polyclonal Antibody
背景資料This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.

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