Anti-KRTAP11-1PolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-KRTAP11-1 Polyclonal Antibody品牌：solarbio | 貨號(hào)：K007937P| 英文名稱 | Anti-KRTAP11-1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | HACL1;HACL-1;KAP11.1 |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:500-2000. |
| 交叉反應(yīng) | Human Mouse |
| 蛋白分子量 | 17kDa |
| Gene ID | 337880 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human KRTAP11-1 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human KRTAP11-1 |
| Swiss Prot | Q8IUC1 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Hair is a structure that is unique to mammals. It plays an important role in the retention of heat, as well as sexual dimorphism, attraction of mates and protection of skin. The major components of hair are -keratins and keratin-associated proteins (KRTAPs or KAPs), each of which are encoded by multigene families. Hair keratins form an intermediate filament (IF) network, which is embedded in an interfilamentous matrix consisting of KRTAPs. KRTAPS comprise three major groups, which are essential for the formation of rigid and resistant hair shafts through disulfide bond cross-linking or hydrophobic interactions with keratins. These groups are designated high cysteine (HS), which includes subfamilies 1, 2, 3, 10, 12, 16, 29 and 31, ultrahigh cysteine, including subfamilies 4, 5, 9, 17, 28, 30, 32 and 33, and high glycine-tyrosine (HGT), which includes subfamilies 6, 7, 8, 19, 20 and 21. In addition, subfamilies 11, 13, 24-27, 29, 34 and 35 have high serine content but relative low cysteine content. After further phylogenetic studies, subfamilies 14 and 15 have been grouped with subfamily 13 and subfamily 22 was combined with subfamily 19. |
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