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Anti-ILF2PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-ILF2 Polyclonal Antibody品牌:solarbio | 貨號:K004279P

英文名稱Anti-ILF2 Polyclonal Antibody
宿主Rabbit
別名NF45;PRO3063
應(yīng)用WB IHC IF
稀釋比例WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反應(yīng) Human Mouse Rat
蛋白分子量43kDa
Gene ID3608
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human ILF2
性狀液體
Public Immunogen RangeRecombinant protein of human ILF2
Subcellular LocationsCytoplasm Nucleus nucleolus
Swiss ProtQ12905
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.

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