Anti-CHRNGPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CHRNG Polyclonal Antibody品牌：solarbio | 貨號：K005529P

英文名稱Anti-CHRNG Polyclonal Antibody
宿主Rabbit
別名ACHRG
應用WB
稀釋比例WB 1:500-2000.
交叉反應 Human Mouse Rat
蛋白分子量58kDa
Gene ID1146
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CHRNG
性狀液體
Public Immunogen RangeRecombinant protein of human CHRNG
Subcellular LocationsCell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse
Swiss ProtP07510
克隆類型 Polyclonal Antibody
背景資料The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.

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