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Anti-FBLN5PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-FBLN5 Polyclonal Antibody品牌:solarbio | 貨號(hào):K007433P

英文名稱Anti-FBLN5 Polyclonal Antibody
宿主Rabbit
別名EVEC;UP50;ADCL2;ARMD3;DANCE;ARCL1A;FIBL-5
應(yīng)用IHC
稀釋比例IHC 1:50-200.
交叉反應(yīng) Human Mouse Rat
蛋白分子量50kDa
Gene ID10516
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human FBLN5
性狀液體
Public Immunogen RangeA synthetic peptide of human FBLN5
Subcellular LocationsCytoplasm
Swiss ProtQ9UBX5
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

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