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Anti-SF1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-SF1 Polyclonal Antibody品牌：solarbio | 貨號：K004516P

英文名稱Anti-SF1 Polyclonal Antibody
宿主Rabbit
別名BBP;D11S636;MBBP;ZCCHC25;ZFM1;ZNF162
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應(yīng) Human Mouse Rat
蛋白分子量68kDa
Gene ID7536
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human SF1
性狀液體
Public Immunogen RangeRecombinant protein of human SF1
Subcellular LocationsNucleus
Swiss ProtQ15637
克隆類型 Polyclonal Antibody
背景資料This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3′ splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.

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