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Anti-RUNX2PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-RUNX2 Polyclonal Antibody品牌：solarbio | 貨號：K003506P

英文名稱Anti-RUNX2 Polyclonal Antibody
宿主Rabbit
別名AML3;CBF-alpha-1;CBFA1;CCD;CCD1;CLCD;OSF-2;OSF2;PEA2aA;PEBP2aA
應(yīng)用WB
稀釋比例WB 1:200-1000.
交叉反應(yīng) Human Mouse
蛋白分子量57kDa
Gene ID860
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human RUNX2
性狀液體
Public Immunogen RangeRecombinant protein of human RUNX2
Subcellular LocationsNucleus
Swiss ProtQ13950
克隆類型 Polyclonal Antibody
背景資料This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

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