Anti-FBXW7PolyclonalAntibody-一抗-抗體-蛋白與免疫-耗材-Bio-Rad伯樂官網(wǎng) |伯樂授權(quán)代理 |伯樂ddPCR| 伯樂Aminex| 伯樂層析填料色譜柱

Anti-FBXW7PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-FBXW7 Polyclonal Antibody品牌：solarbio | 貨號(hào)：K004271P

英文名稱	Anti-FBXW7 Polyclonal Antibody
宿主	Rabbit
別名	AGO;CDC4;FBW6;FBW7;FBX30;FBXO30;FBXW6;SEL-10;SEL10;hAgo;hCdc4
應(yīng)用	WB IHC IF
稀釋比例	WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	80kDa
Gene ID	55294
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human FBXW7
性狀	液體
Public Immunogen Range	Recombinant protein of human FBXW7
Subcellular Locations	Cytoplasm Nucleus nucleolus nucleoplasm
Swiss Prot	Q969H0
克隆類型	Polyclonal Antibody
背景資料	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene’s potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene.

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Anti-FBXW7PolyclonalAntibody-一抗-抗體-蛋白與免疫

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