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Anti-SMAD5PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-SMAD5 Polyclonal Antibody品牌:solarbio | 貨號(hào):K006650P

英文名稱Anti-SMAD5 Polyclonal Antibody
宿主Rabbit
別名DWFC;JV5-1;MADH5
應(yīng)用WB IHC
稀釋比例WB 1:200-1000. IHC 1:25-100.
交叉反應(yīng) Human Mouse Rat
蛋白分子量52kDa
Gene ID4090
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human SMAD5
性狀液體
Public Immunogen RangeRecombinant protein of human SMAD5
Subcellular LocationsCytoplasm
Swiss ProtQ99717
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene.Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). May form trimers with the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit and SMURF1. Interacts with SUV39H1 and SUV39H2. Interacts (via MH2 domain) with LEMD3. Interacts with WWP1.

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