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Anti-Phospho-RPS6KB1-S240/244PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-Phospho-RPS6KB1-S240/244 Polyclonal Antibody品牌：solarbio | 貨號(hào)：K006232P

英文名稱Anti-Phospho-RPS6KB1-S240/244 Polyclonal Antibody
宿主Rabbit
別名S6
應(yīng)用WB IP
稀釋比例WB 1:500-2000. IP 1:50-100.
交叉反應(yīng) Human Mouse
蛋白分子量29kDa
Gene ID6194
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A phospho specific peptide corresponding to residues surrounding S240/244 of human RPS6KB1
性狀液體
Public Immunogen RangeA phospho specific peptide corresponding to residues surrounding S240/244 of human RPS6KB1
Subcellular LocationsCytosol Endoplasmic reticulum Nucleus
Swiss ProtP62753
克隆類型 Polyclonal Antibody
背景資料Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

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