Anti-PSTPIP1PolyclonalAntibody-一抗-抗體-蛋白與免疫-耗材-Bio-Rad伯樂官網(wǎng) |伯樂授權(quán)代理 |伯樂ddPCR| 伯樂Aminex| 伯樂層析填料色譜柱

Anti-PSTPIP1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-PSTPIP1 Polyclonal Antibody品牌：solarbio | 貨號(hào)：K005446P

英文名稱	Anti-PSTPIP1 Polyclonal Antibody
宿主	Rabbit
別名	CD2BP1;CD2BP1L;CD2BP1S;H-PIP;PAPAS;PSTPIP
應(yīng)用	WB IHC
稀釋比例	WB 1:500-2000. IHC 1:50-200.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	48kDa
Gene ID	9051
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human PSTPIP1
性狀	液體
Public Immunogen Range	Recombinant protein of human PSTPIP1
Subcellular Locations	Cell projection Cleavage furrow Cytoplasm cytoskeleton lamellipodium perinuclear region uropodium
Swiss Prot	O43586
克隆類型	Polyclonal Antibody
背景資料	This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response.

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Anti-PSTPIP1PolyclonalAntibody-一抗-抗體-蛋白與免疫

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