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Anti-CIDEAPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CIDEA Polyclonal Antibody品牌：solarbio | 貨號(hào)：K005373P

英文名稱Anti-CIDEA Polyclonal Antibody
宿主Rabbit
別名CIDE-A
應(yīng)用IF
稀釋比例IF 1:50-100.
交叉反應(yīng) Human
蛋白分子量25kDa
Gene ID1149
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CIDEA
性狀液體
Public Immunogen RangeRecombinant protein of human CIDEA
Subcellular LocationsLipid droplet Nucleus
Swiss ProtO60543
克隆類型 Polyclonal Antibody
背景資料This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

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