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Anti-NFKB2PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-NFKB2 Polyclonal Antibody品牌:solarbio | 貨號(hào):K003592P

英文名稱Anti-NFKB2 Polyclonal Antibody
宿主Rabbit
別名CVID10;H2TF1;LYT-10;LYT10;NF-kB2;p100;p49/p100;p52
應(yīng)用WB IHC IF
稀釋比例WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反應(yīng) Human Mouse Rat
蛋白分子量97kDa
Gene ID4791
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human NFKB2
性狀液體
Public Immunogen RangeA synthetic peptide of human NFKB2
Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ00653
克隆類型 Polyclonal Antibody
背景資料This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

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