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Anti-ALKBH2PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-ALKBH2 Polyclonal Antibody品牌：solarbio | 貨號(hào)：K006863P

英文名稱Anti-ALKBH2 Polyclonal Antibody
宿主Rabbit
別名ABH2
應(yīng)用WB
稀釋比例WB 1:500-2000.
交叉反應(yīng) Human Mouse
蛋白分子量29kDa
Gene ID121642
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human ALKBH2
性狀液體
Public Immunogen RangeRecombinant protein of human ALKBH2
Subcellular LocationsNucleus
Swiss ProtQ6NS38
克隆類(lèi)型 Polyclonal Antibody
背景資料The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

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