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Anti-DBIPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-DBI Polyclonal Antibody品牌:solarbio | 貨號:K003948P

英文名稱Anti-DBI Polyclonal Antibody
宿主Rabbit
別名ACBD1;ACBP;CCK-RP;EP
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應(yīng) Human Mouse Rat
蛋白分子量10kDa
Gene ID1622
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human DBI
性狀液體
Public Immunogen RangeRecombinant protein of human DBI
Subcellular LocationsEndoplasmic reticulum Golgi apparatus
Swiss ProtP07108
克隆類型 Polyclonal Antibody
背景資料This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

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