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Anti-MAFAPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-MAFA Polyclonal Antibody品牌：solarbio | 貨號(hào)：K007926P

英文名稱(chēng)Anti-MAFA Polyclonal Antibody
宿主Rabbit
別名hMafA;RIPE3b1
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:25-100.
交叉反應(yīng) Human Mouse
蛋白分子量37kDa
Gene ID389692
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human MAFA
性狀液體
Public Immunogen RangeA synthetic peptide of human MAFA
Subcellular LocationsNucleus
Swiss ProtQ8NHW3
克隆類(lèi)型 Polyclonal Antibody
背景資料Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.

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