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Anti-F7PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-F7 Polyclonal Antibody品牌：solarbio | 貨號：K008248P

英文名稱Anti-F7 Polyclonal Antibody
宿主Rabbit
別名SPCA
應用WB IHC
稀釋比例WB 1:500-2000. IHC 1:25-100.
交叉反應 Human Mouse
蛋白分子量49kDa
Gene ID2155
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human F7
性狀液體
Public Immunogen RangeRecombinant protein of human F7
Subcellular LocationsCytoplasm
Swiss ProtP08709
克隆類型 Polyclonal Antibody
背景資料This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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