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Anti-ACAD11PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-ACAD11 Polyclonal Antibody品牌:solarbio | 貨號:K008273P

英文名稱Anti-ACAD11 Polyclonal Antibody
宿主Rabbit
別名ACAD-11
應(yīng)用WB IHC
稀釋比例WB 1:200-1000. IHC 1:15-50.
交叉反應(yīng) Human Rat
蛋白分子量87kDa
Gene ID84129
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human ACAD11
性狀液體
Public Immunogen RangeRecombinant protein of human ACAD11
Subcellular LocationsCytoplasm
Swiss ProtQ709F0
克隆類型 Polyclonal Antibody
背景資料The deduced full-lengthACAD11protein contains an N-terminal aminoglycoside phosphotransferase domain, followed by a mitochondria localization signal and ACAD N-terminal, middle, and C-terminal domains. It also has a glycosylation site and a C-terminal peroxisome-targeting signal. The ACAD domain contains a catalytic aspartate rather than the catalytic glutamate found in most other ACADs. Real-time RT-PCR detected variableACAD11expression in all tissues examined, with highest expression in adult brain, followed by heart, liver, spinal cord, and kidney. Western blot analysis of fractionated human cerebellum and kidney revealed thatACAD11associated with mitochondrial membranes, but not mitochondrial matrix. Immunohistochemical analysis showed thatACAD11colocalized with a mitochondrial marker in human neuroblastoma cells.

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