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Anti-CASP14PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CASP14 Polyclonal Antibody品牌：solarbio | 貨號：K004598P

英文名稱Anti-CASP14 Polyclonal Antibody
宿主Rabbit
別名ARCI12
應用WB IF
稀釋比例WB 1:500-2000. IF 1:10-100.
交叉反應 Human Mouse Rat
蛋白分子量28kDa
Gene ID23581
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CASP14
性狀液體
Public Immunogen RangeRecombinant protein of human CASP14
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP31944
克隆類型 Polyclonal Antibody
背景資料This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

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