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Anti-PEX5PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-PEX5 Polyclonal Antibody品牌：solarbio | 貨號：K004208P

英文名稱	Anti-PEX5 Polyclonal Antibody
宿主	Rabbit
別名	PBD2A;PBD2B;PTS1-BP;PTS1R;PXR1;RCDP5
應用	WB IHC IF
稀釋比例	WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反應	Human Mouse Rat
蛋白分子量	71kDa
Gene ID	5830
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human PEX5
性狀	液體
Public Immunogen Range	Recombinant protein of human PEX5
Subcellular Locations	Cytoplasm Peripheral membrane protein Peroxisome membrane
Swiss Prot	P50542
克隆類型	Polyclonal Antibody
背景資料	The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

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