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Anti-AGR2PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-AGR2 Polyclonal Antibody品牌:solarbio | 貨號(hào):K004983P

英文名稱Anti-AGR2 Polyclonal Antibody
宿主Rabbit
別名AG-2;AG2;GOB-4;HAG-2;HEL-S-116;HPC8;PDIA17;XAG-2
應(yīng)用WB
稀釋比例WB 1:500-2000.
交叉反應(yīng) Human Mouse Rat
蛋白分子量20kDa
Gene ID10551
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human AGR2
性狀液體
Public Immunogen RangeRecombinant protein of human AGR2
Subcellular LocationsEndoplasmic reticulum Secreted
Swiss ProtO95994
克隆類型 Polyclonal Antibody
背景資料This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.

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