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Anti-SYT17PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-SYT17 Polyclonal Antibody品牌:solarbio | 貨號:K006837P

英文名稱Anti-SYT17 Polyclonal Antibody
宿主Rabbit
別名sytXVII
應用WB IHC
稀釋比例WB 1:200-1000. IHC 1:50-200.
交叉反應 Human Mouse Rat
蛋白分子量54kDa
Gene ID51760
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human SYT17
性狀液體
Public Immunogen RangeRecombinant protein of human SYT17
Subcellular LocationsCytoplasm
Swiss ProtQ9BSW7
克隆類型 Polyclonal Antibody
背景資料Synaptotagmin XVII (SytXVII), also known as Synaptotagmin-17 (SYT17) or Protein B/K, is a 474 amino acid peripheral membrane protein that belongs to the Synaptotagmin family and contains two C2 domains. While expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala, substantia nigra and pituitary), kidney and prostate, Synaptotagmin XVII is also expressed in fetal brain, kidney and lung. The gene that encodes Synaptotagmin XVII contains 100,082 bases and maps to human chromosome 16p12.3. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders, such as giant axonal neuropathy, Rubinstein-Taybi syndrome and Crohn’s disease. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

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