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Anti-CXCR4PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CXCR4 Polyclonal Antibody品牌：solarbio | 貨號：K106446P

英文名稱Anti-CXCR4 Polyclonal Antibody
宿主Rabbit
別名CD184;D2S201E;FB22;HM89;HSY3RR;LAP-3;LAP3;LCR1;LESTR;NPY3R;NPYR;NPYRL;NPYY3R;WHIM;WHIMS
應(yīng)用WB
稀釋比例WB 1:3000.
交叉反應(yīng) Human Mouse Rat
蛋白分子量48kDa
Gene ID7852
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human CXCR4
性狀液體
Public Immunogen RangeA synthetic peptide of human CXCR4
Subcellular LocationsCell junction Cell membrane Early endosome Late endosome Lysosome Multi-pass membrane protein
Swiss ProtP61073
克隆類型 Polyclonal Antibody
背景資料Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

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