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Anti-ANTXR1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-ANTXR1 Polyclonal Antibody品牌：solarbio | 貨號：K008074P

英文名稱Anti-ANTXR1 Polyclonal Antibody
宿主Rabbit
別名ATR;TEM8
應(yīng)用WB IHC
稀釋比例WB 1:200-1000. IHC 1:25-100.
交叉反應(yīng) Human Mouse Rat
蛋白分子量63kDa
Gene ID84168
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human ANTXR1
性狀液體
Public Immunogen RangeRecombinant protein of human ANTXR1
Subcellular LocationsCytoplasm
Swiss ProtQ9H6X2
克隆類型 Polyclonal Antibody
背景資料This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

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