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Anti-PSMD8PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-PSMD8 Polyclonal Antibody品牌：solarbio | 貨號：K006823P

英文名稱Anti-PSMD8 Polyclonal Antibody
宿主Rabbit
別名S14;p31;HIP6;HYPF;Nin1p;Rpn12
應(yīng)用IHC
稀釋比例IHC 1:50-200.
交叉反應(yīng) Human Mouse
蛋白分子量40kDa
Gene ID5714
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human PSMD8
性狀液體
Public Immunogen RangeRecombinant protein of human PSMD8
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP48556
克隆類型 Polyclonal Antibody
背景資料The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.

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