Anti-FBXO32PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-FBXO32 Polyclonal Antibody品牌：solarbio | 貨號：K006787P

英文名稱Anti-FBXO32 Polyclonal Antibody
宿主Rabbit
別名Fbx32;MAFbx
應用WB IHC
稀釋比例WB 1:1000-5000. IHC 1:50-200.
交叉反應 Human Mouse Rat
蛋白分子量42kDa
Gene ID114907
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human FBXO32
性狀液體
Public Immunogen RangeRecombinant protein of human FBXO32
Subcellular LocationsNucleus Cytoplasm
Swiss ProtQ969P5
克隆類型 Polyclonal Antibody
背景資料This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

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