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Anti-ICOSPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-ICOS Polyclonal Antibody品牌：solarbio | 貨號：K006766P

英文名稱Anti-ICOS Polyclonal Antibody
宿主Rabbit
別名AILIM;CD278;CVID1
應(yīng)用IHC
稀釋比例IHC 1:20-100.
交叉反應(yīng) Human
蛋白分子量23kDa
Gene ID29851
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human ICOS
性狀液體
Public Immunogen RangeRecombinant protein of human ICOS
Subcellular LocationsCell membrane Cytoplasm
Swiss ProtQ9Y6W8
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.

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