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Anti-CRTAMPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CRTAM Polyclonal Antibody品牌：solarbio | 貨號：K006716P

英文名稱Anti-CRTAM Polyclonal Antibody
宿主Rabbit
別名CD355
應(yīng)用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應(yīng) Human
蛋白分子量45kDa
Gene ID56253
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CRTAM
性狀液體
Public Immunogen RangeRecombinant protein of human CRTAM
Subcellular Locationscytoplasm
Swiss ProtO95727
克隆類型 Polyclonal Antibody
背景資料Class-I MHC-restricted T cell associated molecule (CRTAM) is a receptor that is primarily expressed on activated cytotoxic lymphocytes, where it may play a role in their adhesion, interaction or migration. It is one of the most highly expressed surface markers detected on activated human NK T cells and CD8 T cells, suggesting its use as a diagnostic tool in various human viral and autoimmune diseases. CRTAM binds nectin-like protein 2 (necl2), which is involved in IL-22 expression regulation. This Necl2/CRTAM molecular pair may regulate cell/cell interactions and may play a role in neuronal interactions. CRTAM is also highly expressed in Purkinje neurons in the cerebellum.

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