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Anti-CSE1LPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CSE1L Polyclonal Antibody品牌：solarbio | 貨號：K006036P

英文名稱Anti-CSE1L Polyclonal Antibody
宿主Rabbit
別名CAS;CSE1;XPO2
應(yīng)用WB
稀釋比例WB 1:500-2000.
交叉反應(yīng) Human
蛋白分子量110kDa
Gene ID1434
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human CSE1L
性狀液體
Public Immunogen RangeA synthetic peptide of human CSE1L
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP55060
克隆類型 Polyclonal Antibody
背景資料Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.

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