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Anti-PLOD1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-PLOD1 Polyclonal Antibody品牌:solarbio | 貨號:K005553P

英文名稱Anti-PLOD1 Polyclonal Antibody
宿主Rabbit
別名EDS6;LH;LH1;LLH;PLOD
應用WB IF
稀釋比例WB 1:500-2000. IF 1:50-200.
交叉反應 Human Mouse
蛋白分子量84kDa
Gene ID5351
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human PLOD1
性狀液體
Public Immunogen RangeRecombinant protein of human PLOD1
Subcellular LocationsLumenal side Peripheral membrane protein Rough endoplasmic reticulum membrane
Swiss ProtQ02809
克隆類型 Polyclonal Antibody
背景資料Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.

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