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Anti-MT-ND1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-MT-ND1 Polyclonal Antibody品牌:solarbio | 貨號:K007773P

英文名稱Anti-MT-ND1 Polyclonal Antibody
宿主Rabbit
別名MTND1;ND1
應用WB IHC
稀釋比例WB 1:200-1000. IHC 1:50-200.
交叉反應 Human Mouse Rat
蛋白分子量36kDa
Gene ID4535
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human MT-ND1
性狀液體
Public Immunogen RangeA synthetic peptide of human MT-ND1
Subcellular LocationsCytoplasm
Swiss ProtP03886
克隆類型 Polyclonal Antibody
背景資料NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.

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